The Guide to Pharmacology Ontology

The Guide to Pharmacoloty Ontoloty (GTPO) is used to define the entities which appear in the Guide to Pharmacology RDF representation. It is based on the Guide to Pharmacology glossary of terms.

Classes

action^c back to ToC or Class ToC

IRI: http://rdf.guidetopharmacology.org/ns/gtpo#Action

Class describing different interaction actions, defined by Guide to Pharmacology

has sub-classes: activation action^c, agonist action^c, antagonist action^c, biased agonist action^c, binding action^c, biphasic action^c, competitive action^c, feedback inhibition action^c, full agonist action^c, inhibition action^c, inverse agonist action^c, irreversible agonist action^c, irreversible inhibition action^c, mixed action^c, negative action^c, neutral action^c, no action^c, non competitive action^c, partial agonist action^c, pore blocker action^c, positive action^c, potentiation action^c, slows inactivation action^c, unknown^c, voltage dependent inbibition action^c
is in range of: has action^op

activation action^c back to ToC or Class ToC

IRI: http://rdf.guidetopharmacology.org/ns/gtpo#ActivationAction

has super-classes: action^c

activator interaction^c back to ToC or Class ToC

IRI: http://rdf.guidetopharmacology.org/ns/gtpo#ActivatorInteraction

has super-classes: interaction^c

agonist action^c back to ToC or Class ToC

IRI: http://rdf.guidetopharmacology.org/ns/gtpo#AgonistAction

has super-classes: action^c

agonist interaction^c back to ToC or Class ToC

IRI: http://rdf.guidetopharmacology.org/ns/gtpo#AgonistInteraction

has super-classes: interaction^c

allosteric modulator interaction^c back to ToC or Class ToC

IRI: http://rdf.guidetopharmacology.org/ns/gtpo#AllostericModulatorInteraction

has super-classes: interaction^c

annotated awaiting review^c back to ToC or Class ToC

IRI: http://rdf.guidetopharmacology.org/ns/gtpo#AnnotatedAwaitingReview

has super-classes: annotation status^c

annotated expert reviewed^c back to ToC or Class ToC

IRI: http://rdf.guidetopharmacology.org/ns/gtpo#AnnotatedExpertReviewed

has super-classes: annotation status^c

annotation status^c back to ToC or Class ToC

IRI: http://rdf.guidetopharmacology.org/ns/gtpo#AnnotationStatus

Class describing annotation status of targets, defined by Guide to Pharmacology

has sub-classes: annotated awaiting review^c, annotated expert reviewed^c, under development^c
is in range of: has annotation status^op

antagonist action^c back to ToC or Class ToC

IRI: http://rdf.guidetopharmacology.org/ns/gtpo#AntagonistAction

has super-classes: action^c

antagonist interaction^c back to ToC or Class ToC

IRI: http://rdf.guidetopharmacology.org/ns/gtpo#AntagonistInteraction

has super-classes: interaction^c

antibody interaction^c back to ToC or Class ToC

IRI: http://rdf.guidetopharmacology.org/ns/gtpo#AntibodyInteraction

has super-classes: interaction^c
is disjoint with: inorganic ligand^c, metabolite ligand^c, natural product ligand^c, peptide ligand^c, synthetic organic ligand^c

antibody ligand^c back to ToC or Class ToC

IRI: http://rdf.guidetopharmacology.org/ns/gtpo#AntibodyLigand

has super-classes: ligand^c

biased agonist action^c back to ToC or Class ToC

IRI: http://rdf.guidetopharmacology.org/ns/gtpo#BiasedAgonistAction

has super-classes: action^c

binding action^c back to ToC or Class ToC

IRI: http://rdf.guidetopharmacology.org/ns/gtpo#BindingAction

has super-classes: action^c

biphasic action^c back to ToC or Class ToC

IRI: http://rdf.guidetopharmacology.org/ns/gtpo#BiphasicAction

has super-classes: action^c

catalytic receptor target family^c back to ToC or Class ToC

IRI: http://rdf.guidetopharmacology.org/ns/gtpo#CatalyticReceptorTargetFamily

has super-classes: target family^c
is disjoint with: enzyme target family^c, g protein coupled receptor target family^c, grouping target family^c, ligand gated ion channel target family^c, ligand target family^c, nuclear hormone receptor target family^c, other ion channel target family^c, other protein target family^c, transporter target family^c, voltage gated ion channel target family^c

channel blocker interaction^c back to ToC or Class ToC

IRI: http://rdf.guidetopharmacology.org/ns/gtpo#ChannelBlockerInteraction

has super-classes: interaction^c

competitive action^c back to ToC or Class ToC

IRI: http://rdf.guidetopharmacology.org/ns/gtpo#CompetitiveAction

has super-classes: action^c

enzyme target family^c back to ToC or Class ToC

IRI: http://rdf.guidetopharmacology.org/ns/gtpo#EnzymeTargetFamily

has super-classes: target family^c
is disjoint with: catalytic receptor target family^c, g protein coupled receptor target family^c, grouping target family^c, ligand gated ion channel target family^c, ligand target family^c, nuclear hormone receptor target family^c, other ion channel target family^c, other protein target family^c, transporter target family^c, voltage gated ion channel target family^c

feedback inhibition action^c back to ToC or Class ToC

IRI: http://rdf.guidetopharmacology.org/ns/gtpo#FeedbackInhibitionAction

has super-classes: action^c

full agonist action^c back to ToC or Class ToC

IRI: http://rdf.guidetopharmacology.org/ns/gtpo#FullAgonistAction

has super-classes: action^c

g protein coupled receptor target family^c back to ToC or Class ToC

IRI: http://rdf.guidetopharmacology.org/ns/gtpo#GProteinCoupledReceptorTargetFamily

has super-classes: target family^c
is disjoint with: catalytic receptor target family^c, enzyme target family^c, grouping target family^c, ligand gated ion channel target family^c, ligand target family^c, nuclear hormone receptor target family^c, other ion channel target family^c, other protein target family^c, transporter target family^c, voltage gated ion channel target family^c

gating inhibitor interaction^c back to ToC or Class ToC

IRI: http://rdf.guidetopharmacology.org/ns/gtpo#GatingInhibitorInteraction

has super-classes: interaction^c

grouping target family^c back to ToC or Class ToC

IRI: http://rdf.guidetopharmacology.org/ns/gtpo#GroupingTargetFamily

has super-classes: target family^c
is disjoint with: catalytic receptor target family^c, enzyme target family^c, g protein coupled receptor target family^c, ligand gated ion channel target family^c, ligand target family^c, nuclear hormone receptor target family^c, other ion channel target family^c, other protein target family^c, transporter target family^c, voltage gated ion channel target family^c

inhibition action^c back to ToC or Class ToC

IRI: http://rdf.guidetopharmacology.org/ns/gtpo#InhibitionAction

has super-classes: action^c

inhibitor interaction^c back to ToC or Class ToC

IRI: http://rdf.guidetopharmacology.org/ns/gtpo#InhibitorInteraction

has super-classes: interaction^c

inorganic ligand^c back to ToC or Class ToC

IRI: http://rdf.guidetopharmacology.org/ns/gtpo#InorganicLigand

has super-classes: ligand^c
is disjoint with: antibody interaction^c, metabolite ligand^c, natural product ligand^c, peptide ligand^c, synthetic organic ligand^c

interaction^c back to ToC or Class ToC

IRI: http://rdf.guidetopharmacology.org/ns/gtpo#Interaction

Class describing the interactions between chemicals and proteins stored in the Guide to Pharmacology data

has sub-classes: activator interaction^c, agonist interaction^c, allosteric modulator interaction^c, antagonist interaction^c, antibody interaction^c, channel blocker interaction^c, gating inhibitor interaction^c, inhibitor interaction^c, subunit specific interaction^c
is in domain of: has action^op, has affinity^op, has high value^dp, has ligand^op, has low value^dp, has median value^dp, has reference^op, has target^op

inverse agonist action^c back to ToC or Class ToC

IRI: http://rdf.guidetopharmacology.org/ns/gtpo#InverseAgonistAction

has super-classes: action^c

irreversible agonist action^c back to ToC or Class ToC

IRI: http://rdf.guidetopharmacology.org/ns/gtpo#IrreversibleAgonistAction

has super-classes: action^c

irreversible inhibition action^c back to ToC or Class ToC

IRI: http://rdf.guidetopharmacology.org/ns/gtpo#IrreversibleInhibitionAction

has super-classes: action^c

ligand^c back to ToC or Class ToC

IRI: http://rdf.guidetopharmacology.org/ns/gtpo#Ligand

Class describing the chemicals stored in the Guide to Pharmacology data

has sub-classes: antibody ligand^c, inorganic ligand^c, metabolite ligand^c, natural product ligand^c, peptide ligand^c, synthetic organic ligand^c
is in domain of: approved^dp, canonical s m i l e s^dp, comment^dp, in ch i i d^dp, in ch i k e y^dp, isomeric s m i l e s^dp, iupac name^dp, ligand name^dp, synonym^dp
is in range of: has ligand^op

ligand gated ion channel target family^c back to ToC or Class ToC

IRI: http://rdf.guidetopharmacology.org/ns/gtpo#LigandGatedIonChannelTargetFamily

has super-classes: target family^c
is disjoint with: catalytic receptor target family^c, enzyme target family^c, g protein coupled receptor target family^c, grouping target family^c, ligand target family^c, nuclear hormone receptor target family^c, other ion channel target family^c, other protein target family^c, transporter target family^c, voltage gated ion channel target family^c

ligand target family^c back to ToC or Class ToC

IRI: http://rdf.guidetopharmacology.org/ns/gtpo#LigandTargetFamily

has super-classes: target family^c
is disjoint with: catalytic receptor target family^c, enzyme target family^c, g protein coupled receptor target family^c, grouping target family^c, ligand gated ion channel target family^c, nuclear hormone receptor target family^c, other ion channel target family^c, other protein target family^c, transporter target family^c, voltage gated ion channel target family^c

metabolite ligand^c back to ToC or Class ToC

IRI: http://rdf.guidetopharmacology.org/ns/gtpo#MetaboliteLigand

has super-classes: ligand^c
is disjoint with: antibody interaction^c, inorganic ligand^c, natural product ligand^c, peptide ligand^c, synthetic organic ligand^c

mixed action^c back to ToC or Class ToC

IRI: http://rdf.guidetopharmacology.org/ns/gtpo#MixedAction

has super-classes: action^c

natural product ligand^c back to ToC or Class ToC

IRI: http://rdf.guidetopharmacology.org/ns/gtpo#NaturalProductLigand

has super-classes: ligand^c
is disjoint with: antibody interaction^c, inorganic ligand^c, metabolite ligand^c, peptide ligand^c, synthetic organic ligand^c

negative action^c back to ToC or Class ToC

IRI: http://rdf.guidetopharmacology.org/ns/gtpo#NegativeAction

has super-classes: action^c

neutral action^c back to ToC or Class ToC

IRI: http://rdf.guidetopharmacology.org/ns/gtpo#NeutralAction

has super-classes: action^c

no action^c back to ToC or Class ToC

IRI: http://rdf.guidetopharmacology.org/ns/gtpo#NoAction

has super-classes: action^c

non competitive action^c back to ToC or Class ToC

IRI: http://rdf.guidetopharmacology.org/ns/gtpo#NonCompetitiveAction

has super-classes: action^c

nuclear hormone receptor target family^c back to ToC or Class ToC

IRI: http://rdf.guidetopharmacology.org/ns/gtpo#NuclearHormoneReceptorTargetFamily

has super-classes: target family^c
is disjoint with: catalytic receptor target family^c, enzyme target family^c, g protein coupled receptor target family^c, grouping target family^c, ligand gated ion channel target family^c, ligand target family^c, other ion channel target family^c, other protein target family^c, transporter target family^c, voltage gated ion channel target family^c

other ion channel target family^c back to ToC or Class ToC

IRI: http://rdf.guidetopharmacology.org/ns/gtpo#OtherIonChannelTargetFamily

has super-classes: target family^c
is disjoint with: catalytic receptor target family^c, enzyme target family^c, g protein coupled receptor target family^c, grouping target family^c, ligand gated ion channel target family^c, ligand target family^c, nuclear hormone receptor target family^c, other protein target family^c, transporter target family^c, voltage gated ion channel target family^c

other protein target family^c back to ToC or Class ToC

IRI: http://rdf.guidetopharmacology.org/ns/gtpo#OtherProteinTargetFamily

has super-classes: target family^c
is disjoint with: catalytic receptor target family^c, enzyme target family^c, g protein coupled receptor target family^c, grouping target family^c, ligand gated ion channel target family^c, ligand target family^c, nuclear hormone receptor target family^c, other ion channel target family^c, transporter target family^c, voltage gated ion channel target family^c

partial agonist action^c back to ToC or Class ToC

IRI: http://rdf.guidetopharmacology.org/ns/gtpo#PartialAgonistAction

has super-classes: action^c

peptide ligand^c back to ToC or Class ToC

IRI: http://rdf.guidetopharmacology.org/ns/gtpo#PeptideLigand

has super-classes: ligand^c
is disjoint with: antibody interaction^c, inorganic ligand^c, metabolite ligand^c, natural product ligand^c, synthetic organic ligand^c

pore blocker action^c back to ToC or Class ToC

IRI: http://rdf.guidetopharmacology.org/ns/gtpo#PoreBlockerAction

has super-classes: action^c

positive action^c back to ToC or Class ToC

IRI: http://rdf.guidetopharmacology.org/ns/gtpo#PositiveAction

has super-classes: action^c

potentiation action^c back to ToC or Class ToC

IRI: http://rdf.guidetopharmacology.org/ns/gtpo#PotentiationAction

has super-classes: action^c

slows inactivation action^c back to ToC or Class ToC

IRI: http://rdf.guidetopharmacology.org/ns/gtpo#SlowsInactivationAction

has super-classes: action^c

subunit specific interaction^c back to ToC or Class ToC

IRI: http://rdf.guidetopharmacology.org/ns/gtpo#SubunitSpecificInteraction

has super-classes: interaction^c

synthetic organic ligand^c back to ToC or Class ToC

IRI: http://rdf.guidetopharmacology.org/ns/gtpo#SyntheticOrganicLigand

has super-classes: ligand^c
is disjoint with: antibody interaction^c, inorganic ligand^c, metabolite ligand^c, natural product ligand^c, peptide ligand^c

target^c back to ToC or Class ToC

IRI: http://rdf.guidetopharmacology.org/ns/gtpo#Target

Class describing the different proteins stored in the Guide to Pharmacology data

is in domain of: has annotation status^op, has target family^op, nomenclature^dp
is in range of: has target^op

target family^c back to ToC or Class ToC

IRI: http://rdf.guidetopharmacology.org/ns/gtpo#TargetFamily

Class describing families of proteins stored in the Guide to Pharmacology data

has sub-classes: catalytic receptor target family^c, enzyme target family^c, g protein coupled receptor target family^c, grouping target family^c, ligand gated ion channel target family^c, ligand target family^c, nuclear hormone receptor target family^c, other ion channel target family^c, other protein target family^c, transporter target family^c, voltage gated ion channel target family^c
is in domain of: target family name^dp
is in range of: has target family^op

transporter target family^c back to ToC or Class ToC

IRI: http://rdf.guidetopharmacology.org/ns/gtpo#TransporterTargetFamily

has super-classes: target family^c
is disjoint with: catalytic receptor target family^c, enzyme target family^c, g protein coupled receptor target family^c, grouping target family^c, ligand gated ion channel target family^c, ligand target family^c, nuclear hormone receptor target family^c, other ion channel target family^c, other protein target family^c, voltage gated ion channel target family^c

under development^c back to ToC or Class ToC

IRI: http://rdf.guidetopharmacology.org/ns/gtpo#UnderDevelopment

has super-classes: annotation status^c

unknown^c back to ToC or Class ToC

IRI: http://rdf.guidetopharmacology.org/ns/gtpo#Unknown

has super-classes: action^c

voltage dependent inbibition action^c back to ToC or Class ToC

IRI: http://rdf.guidetopharmacology.org/ns/gtpo#VoltageDependentInbibitionAction

has super-classes: action^c

voltage gated ion channel target family^c back to ToC or Class ToC

IRI: http://rdf.guidetopharmacology.org/ns/gtpo#VoltageGatedIonChannelTargetFamily

has super-classes: target family^c
is disjoint with: catalytic receptor target family^c, enzyme target family^c, g protein coupled receptor target family^c, grouping target family^c, ligand gated ion channel target family^c, ligand target family^c, nuclear hormone receptor target family^c, other ion channel target family^c, other protein target family^c, transporter target family^c

Data Properties

approved^dp back to ToC or Data Property ToC

IRI: http://rdf.guidetopharmacology.org/ns/gtpo#approved

Approval status of a ligand

has domain: ligand^c
has range: boolean

canonical s m i l e s^dp back to ToC or Data Property ToC

IRI: http://rdf.guidetopharmacology.org/ns/gtpo#canonicalSMILES

canonical SMILES, describing a ligand

has domain: ligand^c
has range: string

comment^dp back to ToC or Data Property ToC

IRI: http://rdf.guidetopharmacology.org/ns/gtpo#comment

Guide to Pharmacology comments on a ligand

has domain: ligand^c
has range: string

has high value^dp back to ToC or Data Property ToC

IRI: http://rdf.guidetopharmacology.org/ns/gtpo#hasHighValue

High value of an interaction affinity, also has low value

has domain: interaction^c
has range: double

has low value^dp back to ToC or Data Property ToC

IRI: http://rdf.guidetopharmacology.org/ns/gtpo#hasLowValue

Low value of an interaction affinity, also has high value

has domain: interaction^c
has range: double

has median value^dp back to ToC or Data Property ToC

IRI: http://rdf.guidetopharmacology.org/ns/gtpo#hasMedianValue

Median value of an interaction affinity

has domain: interaction^c
has range: double

in ch i i d^dp back to ToC or Data Property ToC

IRI: http://rdf.guidetopharmacology.org/ns/gtpo#InChIID

InChI identifier for a ligand

has domain: ligand^c
has range: string

in ch i k e y^dp back to ToC or Data Property ToC

IRI: http://rdf.guidetopharmacology.org/ns/gtpo#InChIKEY

InChI key defining a ligand

has domain: ligand^c
has range: string

isomeric s m i l e s^dp back to ToC or Data Property ToC

IRI: http://rdf.guidetopharmacology.org/ns/gtpo#isomericSMILES

isomeric SMILES, describing a ligand

has domain: ligand^c
has range: string

iupac name^dp back to ToC or Data Property ToC

IRI: http://rdf.guidetopharmacology.org/ns/gtpo#iupacName

name of a ligand, defined by the IUPAC

has domain: ligand^c
has range: string

ligand name^dp back to ToC or Data Property ToC

IRI: http://rdf.guidetopharmacology.org/ns/gtpo#ligandName

the name of a chemical ligand

has domain: ligand^c
has range: string

nomenclature^dp back to ToC or Data Property ToC

IRI: http://rdf.guidetopharmacology.org/ns/gtpo#nomenclature

nomenclature, the name of a target

has domain: target^c
has range: string

synonym^dp back to ToC or Data Property ToC

IRI: http://rdf.guidetopharmacology.org/ns/gtpo#synonym

Synony of a ligand

has domain: ligand^c
has range: string

target family name^dp back to ToC or Data Property ToC

IRI: http://rdf.guidetopharmacology.org/ns/gtpo#targetFamilyName

name for target family

has domain: target family^c
has range: string

This HTML document was obtained by processing the OWL ontology source code through LODE, Live OWL Documentation Environment, developed by Silvio Peroni.

The Guide to Pharmacology Ontology

Abstract

Table of Content

Classes

actionc back to ToC or Class ToC

activation actionc back to ToC or Class ToC

activator interactionc back to ToC or Class ToC

agonist actionc back to ToC or Class ToC

agonist interactionc back to ToC or Class ToC

allosteric modulator interactionc back to ToC or Class ToC

annotated awaiting reviewc back to ToC or Class ToC

annotated expert reviewedc back to ToC or Class ToC

annotation statusc back to ToC or Class ToC

antagonist actionc back to ToC or Class ToC

antagonist interactionc back to ToC or Class ToC

antibody interactionc back to ToC or Class ToC

antibody ligandc back to ToC or Class ToC

biased agonist actionc back to ToC or Class ToC

binding actionc back to ToC or Class ToC

biphasic actionc back to ToC or Class ToC

catalytic receptor target familyc back to ToC or Class ToC

channel blocker interactionc back to ToC or Class ToC

competitive actionc back to ToC or Class ToC

enzyme target familyc back to ToC or Class ToC

feedback inhibition actionc back to ToC or Class ToC

full agonist actionc back to ToC or Class ToC

g protein coupled receptor target familyc back to ToC or Class ToC

gating inhibitor interactionc back to ToC or Class ToC

grouping target familyc back to ToC or Class ToC

inhibition actionc back to ToC or Class ToC

inhibitor interactionc back to ToC or Class ToC

inorganic ligandc back to ToC or Class ToC

interactionc back to ToC or Class ToC

inverse agonist actionc back to ToC or Class ToC

irreversible agonist actionc back to ToC or Class ToC

irreversible inhibition actionc back to ToC or Class ToC

ligandc back to ToC or Class ToC

ligand gated ion channel target familyc back to ToC or Class ToC

ligand target familyc back to ToC or Class ToC

metabolite ligandc back to ToC or Class ToC

mixed actionc back to ToC or Class ToC

natural product ligandc back to ToC or Class ToC

negative actionc back to ToC or Class ToC

neutral actionc back to ToC or Class ToC

no actionc back to ToC or Class ToC

non competitive actionc back to ToC or Class ToC

nuclear hormone receptor target familyc back to ToC or Class ToC

other ion channel target familyc back to ToC or Class ToC

other protein target familyc back to ToC or Class ToC

partial agonist actionc back to ToC or Class ToC

peptide ligandc back to ToC or Class ToC

pore blocker actionc back to ToC or Class ToC

positive actionc back to ToC or Class ToC

potentiation actionc back to ToC or Class ToC

slows inactivation actionc back to ToC or Class ToC

subunit specific interactionc back to ToC or Class ToC

synthetic organic ligandc back to ToC or Class ToC

targetc back to ToC or Class ToC

target familyc back to ToC or Class ToC

transporter target familyc back to ToC or Class ToC

under developmentc back to ToC or Class ToC

unknownc back to ToC or Class ToC

voltage dependent inbibition actionc back to ToC or Class ToC

voltage gated ion channel target familyc back to ToC or Class ToC

Object Properties

has actionop back to ToC or Object Property ToC

has affinityop back to ToC or Object Property ToC

has annotation statusop back to ToC or Object Property ToC

has ligandop back to ToC or Object Property ToC

has refop back to ToC or Object Property ToC

has referenceop back to ToC or Object Property ToC

has speciesop back to ToC or Object Property ToC

has targetop back to ToC or Object Property ToC

has target familyop back to ToC or Object Property ToC

has unitop back to ToC or Object Property ToC

xrefop back to ToC or Object Property ToC